Identification of the Key Genes and Pathways in Esophageal Carcinoma

Table 2

The top 10 up-regulated and top 10 down-regulated DEGs in EC.

Gene ID	Gene symbol	Official full name	FDR
Upregulated (top 10)
1019	CDK4	Cyclin-dependent kinase 4	0.0002252
4605	MYBL2	MYB protooncogene like 2	0.0002252
7203	CCT3	Chaperonin containing TCP1 subunit 3	0.0003378
83461	CDCA3	Cell division cycle associated 3	0.0004504
1033	CDKN3	Cyclin-dependent kinase inhibitor 3	0.0004504
1063	CENPF	Centromere protein F	0.0004729
9156	EXO1	Exonuclease 1	0.0004729
79075	DSCC1	DNA replication and sister chromatid cohesion 1	0.0005405
4751	NEK2	NIMA related kinase 2	0.0005405
Downregulated (top 10)
79875	THSD4	Thrombospondin type 1 domain containing 4	0.0002252
79026	AHNAK	AHNAK nucleoprotein	0.0004729
6493	SIM2	Single-minded family bHLH transcription factor 2	0.0004729
7881	KCNAB1	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1	0.0005405
90865	IL33	Interleukin 33	0.0008812
55287	TMEM40	Transmembrane protein 40	0.0008812
966	CD59	CD59 molecule	0.0015608
5121	PCP4	Purkinje cell protein 4	0.0015608
22885	ABLIM3	Actin binding LIM protein family member 3	0.0016629
3590	IL11RA	Interleukin 11 receptor subunit alpha	0.0016629

EC: esophageal carcinoma; FDR: false discovery rate.