Research Article

Identification of the Key Genes and Pathways in Esophageal Carcinoma

Table 4

GO annotation of downregulated DEGs in EC.

GO IDGO termCount valueFDR

Biological process
GO:0009611Response to wounding651.98E − 083.57E − 05
GO:0042060Wound healing335.75E − 081.04E − 04
GO:0030097Hemopoiesis321.85E − 050.0334238
GO:0007167Enzyme linked receptor protein signaling pathway412.03E − 050.0365533
GO:0030036Actin cytoskeleton organization312.05E − 050.0370181
GO:0048534Hemopoietic or lymphoid organ development342.06E − 050.0372021
GO:0007155Cell adhesion692.10E − 050.0378896
GO:0042692Muscle cell differentiation212.14E − 050.0386651
GO:0022610Biological adhesion692.19E − 050.0394751
GO:0007178Transmembrane receptor protein serine/threonine kinase signaling pathway192.53E − 050.0456886
Cellular component
GO:0015629Actin cytoskeleton365.84E − 060.008305
GO:0005794Golgi apparatus837.36E − 060.0104637
GO:0005856Cytoskeleton1181.23E − 050.0175254
Molecular function
GO:0008092Cytoskeletal protein binding598.55E − 070.0013403

EC: esophageal carcinoma; FDR: false discovery rate.