Research Article
Identification of the Key Genes and Pathways in Esophageal Carcinoma
Table 4
GO annotation of downregulated DEGs in EC.
| GO ID | GO term | Count | value | FDR |
| Biological process | | | | | GO:0009611 | Response to wounding | 65 | 1.98E − 08 | 3.57E − 05 | GO:0042060 | Wound healing | 33 | 5.75E − 08 | 1.04E − 04 | GO:0030097 | Hemopoiesis | 32 | 1.85E − 05 | 0.0334238 | GO:0007167 | Enzyme linked receptor protein signaling pathway | 41 | 2.03E − 05 | 0.0365533 | GO:0030036 | Actin cytoskeleton organization | 31 | 2.05E − 05 | 0.0370181 | GO:0048534 | Hemopoietic or lymphoid organ development | 34 | 2.06E − 05 | 0.0372021 | GO:0007155 | Cell adhesion | 69 | 2.10E − 05 | 0.0378896 | GO:0042692 | Muscle cell differentiation | 21 | 2.14E − 05 | 0.0386651 | GO:0022610 | Biological adhesion | 69 | 2.19E − 05 | 0.0394751 | GO:0007178 | Transmembrane receptor protein serine/threonine kinase signaling pathway | 19 | 2.53E − 05 | 0.0456886 | Cellular component | | | | | GO:0015629 | Actin cytoskeleton | 36 | 5.84E − 06 | 0.008305 | GO:0005794 | Golgi apparatus | 83 | 7.36E − 06 | 0.0104637 | GO:0005856 | Cytoskeleton | 118 | 1.23E − 05 | 0.0175254 | Molecular function | | | | | GO:0008092 | Cytoskeletal protein binding | 59 | 8.55E − 07 | 0.0013403 |
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EC: esophageal carcinoma; FDR: false discovery rate.
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