Table of Contents Author Guidelines Submit a Manuscript
Gastroenterology Research and Practice
Volume 2016, Article ID 2978479, 5 pages
http://dx.doi.org/10.1155/2016/2978479
Research Article

The Relationship between Inflammatory Marker Levels and Hepatitis C Virus Severity

1Department of Clinical Laboratory, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China
2Department of Traditional Chinese Medicine, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China
3Department of Infection Control, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China

Received 9 August 2016; Accepted 8 November 2016

Academic Editor: Amosy M’Koma

Copyright © 2016 Qitian He et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Sharma, M. Carballo, J. J. Feld, and H. L. A. Janssen, “Immigration and viral hepatitis,” Journal of Hepatology, vol. 63, no. 2, pp. 515–522, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Grebely and G. J. Dore, “What is killing people with hepatitis C virus infection?” Seminars in Liver Disease, vol. 31, no. 4, pp. 331–339, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. B. Hajarizadeh, J. Grebely, and G. J. Dore, “Epidemiology and natural history of HCV infection,” Nature Reviews Gastroenterology and Hepatology, vol. 10, no. 9, pp. 553–562, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. B. Ceylan, B. Mete, M. Fincanci et al., “A new model using platelet indices to predict liver fibrosis in patients with chronic hepatitis B infection,” Wiener Klinische Wochenschrift, vol. 125, no. 15-16, pp. 453–460, 2013. View at Publisher · View at Google Scholar · View at Scopus
  5. Y.-F. Liaw, N. Leung, J.-H. Kao et al., “Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update,” Hepatology International, vol. 2, no. 3, pp. 263–283, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. C.-T. Wai, J. K. Greenson, R. J. Fontana et al., “A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C,” Hepatology, vol. 38, no. 2, pp. 518–526, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. R. K. Sterling, E. Lissen, N. Clumeck et al., “Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection,” Hepatology, vol. 43, no. 6, pp. 1317–1325, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. Y. Lou, M. Wang, and W. Mao, “Clinical usefulness of measuring red blood cell distribution width in patients with hepatitis B,” PLoS ONE, vol. 7, no. 5, Article ID e37644, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Cengiz, B. A. Candir, G. Yilmaz, G. Akyol, and S. Ozenirler, “Is increased red cell distribution width an indicating marker of nonalcoholic steatohepatitis and fibrotic stage?” World Journal of Gastroenterology, vol. 19, no. 42, pp. 7412–7418, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. E. Karagoz, A. Ulcay, A. Tanoglu et al., “Clinical usefulness of mean platelet volume and red blood cell distribution width to platelet ratio for predicting the severity of hepatic fibrosis in chronic hepatitis B virus patients,” European Journal of Gastroenterology and Hepatology, vol. 26, no. 12, pp. 1320–1324, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. H. Wang, H. Xu, X. Wang et al., “Red blood cell distribution width to platelet ratio is related to histologic severity of primary biliary cirrhosis,” Medicine, vol. 95, no. 11, article e3114, 2016. View at Publisher · View at Google Scholar
  12. X. Meng, G. Wei, Q. Chang et al., “The platelet-to-lymphocyte ratio, superior to the neutrophil-to-lymphocyte ratio, correlates with hepatitis C virus infection,” International Journal of Infectious Diseases, vol. 45, pp. 72–77, 2016. View at Publisher · View at Google Scholar
  13. O. Abakay, A. Abakay, H. S. Sen, and A. C. Tanrikulu, “The Relationship Between Inflammatory Marker Levels and Pulmonary Tuberculosis Severity,” Inflammation, vol. 38, no. 2, pp. 691–696, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. N. H. Afdhal, “The natural history of hepatitis C,” Seminars in Liver Disease, vol. 24, supplement 2, pp. 3–8, 2004. View at Google Scholar · View at Scopus
  15. B. Chen, B. Ye, J. Zhang, L. Ying, and Y. Chen, “RDW to platelet ratio: a novel noninvasive index for predicting hepatic fibrosis and cirrhosis in chronic hepatitis B,” PLoS ONE, vol. 8, no. 7, Article ID e68780, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. W.-S. Xu, X.-M. Qiu, Q.-S. Ou et al., “Red blood cell distribution width levels correlate with liver fibrosis and inflammation: a noninvasive serum marker panel to predict the severity of fibrosis and inflammation in patients with hepatitis B,” Medicine, vol. 94, no. 10, article e612, 2015. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Huang, C. Yang, K. Wu et al., “Red cell distribution width as a potential index to assess the severity of hepatitis B virus-related liver diseases,” Hepatology Research, vol. 44, no. 14, pp. E464–E470, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. W. Yang, H. Huang, Y. Wang, X. Yu, and Z. Yang, “High red blood cell distribution width is closely associated with nonalcoholic fatty liver disease,” European Journal of Gastroenterology and Hepatology, vol. 26, no. 2, pp. 174–178, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. A. Taefi, C.-C. Huang, K. Kolli, S. Ebrahimi, and M. Patel, “Red cell distribution width to platelet ratio, a useful indicator of liver fibrosis in chronic hepatitis patients,” Hepatology International, vol. 9, no. 3, pp. 454–460, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. L. Jin, X. Li, J. Ye et al., “Value of red blood cell distribution width in assessing the severity of hepatitis C virus-related liver diseases,” Zhonghua Gan Zang Bing Za Zhi, vol. 24, pp. 130–132, 2016. View at Google Scholar
  21. A. Baranova, P. Lal, A. Birerdinc, and Z. M. Younossi, “Non-invasive markers for hepatic fibrosis,” BMC Gastroenterology, vol. 11, article 91, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Derbala, M. E. Elbadri, A. M. Amer et al., “Aspartate transaminase to platelet ratio index in hepatitis C virus and Schistosomiasis coinfection,” World Journal of Gastroenterology, vol. 21, no. 46, pp. 13132–13139, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. G. Lippi, G. Targher, M. Montagnana, G. L. Salvagno, G. Zoppini, and G. C. Guidi, “Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients,” Archives of Pathology and Laboratory Medicine, vol. 133, no. 4, pp. 628–632, 2009. View at Google Scholar · View at Scopus
  24. J. G. McHutchison, M. P. Manns, and D. L. Longo, “Definition and management of anemia in patients infected with hepatitis C virus,” Liver International, vol. 26, no. 4, pp. 389–398, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. W. G. Thompson, T. Meola, M. Lipkin Jr., and M. L. Freedman, “Red cell distribution width, mean corpuscular volume, and transferrin saturation in the diagnosis of iron deficiency,” Archives of Internal Medicine, vol. 148, no. 10, pp. 2128–2130, 1988. View at Publisher · View at Google Scholar · View at Scopus
  26. K. S. Louie, J. M. Micallef, J. M. Pimenta, and U. M. Forssen, “Prevalence of thrombocytopenia among patients with chronic hepatitis C: a systematic review,” Journal of Viral Hepatitis, vol. 18, no. 1, pp. 1–7, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. E. G. Giannini, F. Botta, P. Borro et al., “Application of the platelet count/spleen diameter ratio to rule out the presence of oesophageal varices in patients with cirrhosis: a validation study based on follow-up,” Digestive and Liver Disease, vol. 37, no. 10, pp. 779–785, 2005. View at Publisher · View at Google Scholar · View at Scopus