The Relationship between Inflammatory Marker Levels and Hepatitis C Virus Severity

Table 2

Comparison of demographic, clinical characteristics, and laboratory results between chronic HCV and HCV-related cirrhosis patients.

Characteristics and parameters	Chronic HCV ()	HCV-related cirrhosis ()	value
Gender (male/female)	36/16	29/13	0.985
Age (years)			0.103
WBC count (×10^9/L)			0.004
Hemoglobin (g/L)			<0.001
Platelet count (×10^9/L)			<0.001
Total bilirubin (μmol/L)			<0.001
Total protein (g/L)			0.297
Albumin (g/L)			<0.001
AST (U/L)			0.112
ALT (U/L)			0.777
AAR			<0.001
PT (s)			<0.001
INR			<0.001
Creatinine (μmol/L)			0.381
RDW (%)			<0.001
APRI			<0.001
FIB-4			<0.001
RPR			<0.001
1/PLR			0.002
HCV RNA (IU/mL)			0.605

Data are expressed as or mean ± SD. HCV: hepatitis C virus; AST: aspartate aminotransferase; ALT: alanine aminotransferase; AAR: aspartate aminotransferase to alanine aminotransferase ratio; PT: prothrombin time; INR: international normalized ratio; RDW: red cell distribution width; APRI: aspartate aminotransferase-to-platelet ratio index; FIB-4: fibrosis index based on the 4 factors; RPR: red cell distribution width to platelet ratio; PLR: platelet-lymphocyte ratio.