Research Article

Synergic Interaction of Rifaximin and Mutaflor (Escherichia coli Nissle 1917) in the Treatment of Acetic Acid-Induced Colitis in Rats

Table 3

Influence of Mutaflor (Escherichia coli Nissle 1917), rifaximin, and colitis applied alone or in their combination on the number of Enterococcus spp. identified by qPCR in feces samples.

Experimental groupsThe number of bacteria (CFU/g)

Control3.54 × 107 ± 5.90 × 104
Mutaflor3.23 × 105 ± 5.73 × 
Rifaximin6.88 × 101 ± 3.78 × 
Rifaximin + Mutaflor3.59 × 102 ± 7.69 × 
Colitis + NaCl4.34 × 108 ± 5.68 × 
Colitis + Mutaflor2.45 × 107 ± 3.22 × 
Colitis + rifaximin1.45 × 102 ± 7.26 × 
Colitis + rifaximin + Mutaflor6.34 × 104 ± 7.05 × 

Mean value ± SEM. observations in each experimental group. compared to control; compared to colitis + NaCl; and compared to colitis + Mutaflor.