Clinical Outcomes of Endoscopic Submucosal Dissection for Early Esophageal Squamous Cell Neoplasms: A Retrospective Single-Center Study in China

Table 2

Endoscopic treatment/patients’ clinical course after ESD.

	Combined	Intramucosal invasive ESCC	HGIN	P value
Number of lesions	307	79	228
En bloc resection	287 (93.5%)	70 (88.6%)	217 (95.2%)	0.041
Complete resection	240 (78.2%)	58 (73.4%)	182 (79.8%)	0.235
Resection time (minutes)	60 (40–90)	60 (43–110)	60 (40–90)	0.487
Number of patients	296	79	217
Length of hospitalization (days)	6 (5–7)	6 (5–8)	6 (5–7)	0.351
Follow-up period (months)	30 (13.3)	31 (12.3)	29 (13.8)	0.325
Complications
Perforation	3 (1.0%)	1	3
Bleeding	2 (0.7%)	0	2
Stricture	25 (8.4%)	9	16
Residual	27 (9.1%)	9 (11.4%)	18 (8.3%)	0.413
Recurrence	18 (6.1%)	6 (7.6%)	12 (5.5%)	0.702
Local recurrence	12	5	7
Synchronous recurrence	4	1	3
Metachronous recurrence	2	0	2
Mortality	13	4	9
Cancer-related death	0	0	0

ESD: endoscopic submucosal dissection; ESCC: esophageal squamous cell carcinoma; HGIN: high-grade intraepithelial neoplasia.