Feasibility and Efficacy of S-Adenosyl-L-methionine in Patients with HBV-Related HCC with Different BCLC Stages

Table 1

General information for the included patients at entry.

	BCLC stages A1–A4 ()			BCLC stages B-C ()
	MgiBC + SAMe	MgiBC	value	MgiBC + SAMe	MgiBC	value
Gender (M/F)	83/36	106/31	0.16	192/43	177/29	0.23
Age (years)			0.39			0.81
Liver function
TBIL (umol/L)			0.38			0.07
ALT (U/L)			0.66			0.16
AST (U/L)			0.18			0.34
ALB (g/L)			0.15			0.43
Lesion data
Nodules (1/≥2)	106/13	120/17	0.71	211/24	189/17	0.47
Size (cm)			0.16			0.12
Tumor staging ()
A1~A3	106	120	0.71	—	—	—
A4	13	17		—	—
B	—	—	—	190	167	0.95
C	—	—		45	39
Child-Pugh
Class A/B ()	82/37	103/34	0.26	183/52	165/41	0.56
AFP (ng/mL)			0.56			0.21
Viral load (UI/uL)			0.42			0.45

Child-Pugh class B patients who received symptomatic treatment were considered Child-Pugh class A prior to surgery.