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Gastroenterology Research and Practice
Volume 2016, Article ID 4514687, 5 pages
http://dx.doi.org/10.1155/2016/4514687
Research Article

Tea and Recurrent Clostridium difficile Infection

1Department of Internal Medicine, Novosel Aviation Clinic, Fort Riley, KS, USA
2Department of Gastroenterology, St. Luke's Clinic, Twin Falls, ID, USA
3Department of Internal Medicine, San Antonio Military Medical Center, San Antonio, TX, USA
4Physical Medicine and Rehabilitation, Larkin Community Hospital, South Miami, FL, USA
5Novosel Aviation Clinic, Fort Riley, KS, USA

Received 7 March 2016; Revised 16 July 2016; Accepted 10 August 2016

Academic Editor: Helieh Oz

Copyright © 2016 Martin Oman Evans II et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background and Aims. Studies have shown effects of diet on gut microbiota. We aimed to identify foods associated with recurrent Clostridium difficile infection (CDI). Methods. In this cross-sectional survey, consecutive patients diagnosed with CDI were identified by electronic medical records. Colitis symptoms and positive Clostridium difficile assay were confirmed. Health-care onset-health-care facility associated CDI was excluded. Food surveys were mailed to 411 patients. Survey responses served as the primary outcome measure. Spearman’s rank correlation identified risk factors for CDI recurrence. Results. Surveys were returned by 68 patients. Nineteen patients experienced CDI recurrence. Compared to patients without CDI recurrence, patients with CDI recurrence had more antibiotics prescribed preceding their infection (). Greater numbers of the latter also listed tea (), coffee (), and eggs (), on their 24-hour food recall. Logistic regression identified tea as the only food risk factor for CDI recurrence (adjusted OR: 5.71; 95% CI: 1.26–25.89). Conclusion. The present results indicate a possible association between tea and CDI recurrence. Additional studies are needed to characterize and confirm this association.