Gastroenterology Research and Practice / 2016 / Article / Tab 1

Review Article

Duodenal Rare Neuroendocrine Tumor: Clinicopathological Characteristics of Patients with Gangliocytic Paraganglioma

Table 1

Immunohistochemical findings in each tumor component of gangliocytic paraganglioma.

Immunohistochemical markerEpithelioid cells
Spindle-shaped cellsGanglion-like cells

Bcl-216.7% (2/12)58.33% (7/12)36.36% (4/11)
Calcitonin20.8% (5/24)20.0% (4/20)21.05% (4/19)
CD340% (0/2)33.33% (1/3)0% (0/1)
CD56100% (27/27)50% (9/18)100% (19/19)
Chromogranin A74.8% (98/131)8.8% (9/102)28.9% (28/97)
Cytokeratins58.8% (50/85)6.0% (4/67)3.0% (2/66)
C-kit0% (0/8)0% (0/8)16.7% (4/11)
Corticotropin0% (0/0)0% (0/3)0% (0/2)
Estrogen receptor23.1% (3/13)0% (0/12)0% (0/11)
Gastrin4.5% (3/67)0% (0/62)0% (0/60)
Glucagon6.1% (3/49)0% (0/44)2.3% (1/43)
Insulin4.3% (2/47)0% (0/42)0% (0/41)
Neurofilament21.7% (15/69)69.1% (47/68)27.3% (18/66)
Neuron-specific enolase95.7% (90/94)85.0% (68/80)87.0% (80/92)
p530% (0/13)0% (0/12)0% (0/11)
Progesterone receptor93.3% (14/15)0% (0/12)0% (0/12)
Pancreatic polypeptide91.5% (86/94)0% (0/83)32.1% (27/84)
S-10010.2% (13/128)96.6% (144/149)23.9% (28/117)
Serotonin20.0% (12/60)1.5% (1/66)16.7% (9/54)
Somatostatin82.6% (76/92)8.7% (6/69)51.3% (41/80)
Synaptophysin96.2% (76/79)54.4% (31/57)98.4% (61/62)
Vimentin37.5% (3/8)60.0% (3/5)25.0% (1/4)
Vasoactive intestinal peptide12.1% (4/33)13.3% (4/30)10.3% (3/29)

The positive or negative rates in the extracted cases of duodenal gangliocytic paraganglioma are summarized. Listing in alphabetical number.

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