Bowel Perforation in Premature Infants with Necrotizing Enterocolitis: Risk Factors and Outcomes
Table 2
Clinical characteristics in NEC infants with and without bowel perforation.
Perforated NEC group ()
Nonperforated NEC group ()
Onset age (d)
10.0 (7.50–22.25)
7.0 (2–14)
0.40
Time for the first enteral feeding (d)
3.8 ± 3.16
5.8 ± 3.48
0.08
Speed of the increase of milk intake (cc/kg/d)
4.20 ± 3.65
7.02 ± 6.48
0.07
Abdominal distension
10 (100.00)
35 (74.40)
0.17
Vomiting
6 (60.00)
19 (40.40)
0.43
Stool RBCs
3 (30.00)
18 (38.30)
0.89
CHD
4 (40.00)
9 (19.10)
0.31
Sepsis
4 (40.00)
4 (8.50)
0.04
Apnea
6 (60.00)
7 (14.80)
<0.01
ICH
2 (20.00)
2 (4.20)
0.14
Shock
3 (30.00)
1 (2.10)
0.02
RDS
3 (30.00)
7 (14.80)
0.49
Neonatal pneumonia
5 (50.00)
22 (46.80)
1.00
Blood transfusion
4 (40.00)
6 (12.70)
0.12
Mechanical ventilation
7 (70.00)
14 (29.70)
0.04
Note: data were expressed as median (interquartile range); data were expressed as mean ± SD; data were expressed as the number (percentage within the group); compared to the nonperforated NEC group. CHD, congenital heart disease; ICH, intracranial hemorrhage; NEC, necrotizing enterocolitis; RDS, respiratory distress syndrome.
