Review Article

Ultrasonic Dissection versus Conventional Dissection for Pancreatic Surgery: A Meta-Analysis

Table 1

Characteristics of the included studies.

Author Year CountryStudy designStudy intervalAge (years)Cases Type of surgeryUltrasonic deviceDefinition of pancreatic fistulaQuality score
UDCDUD (M/F)CD (M/F)

Suzuki et al. [15]1999JapanRCT1994–199857.758.527 (18/9)31 (18/13)DPCUSAAn external discharge of pancreatic fluid (>7 d) with an amylase level of >3 times the serum level2/5

Sugo et al. [16]2001JapanRetro.1994–200061.756.711 (6/5)20 (12/8)DPHSAn external discharge of pancreatic fluid (>7 d) or a high level of amylase in the drainage fluid (>3 times the serum level) on day 7 after surgery15/24

Satoi et al. [17]2011JapanPNR2009-2010726413 (8/5)13 (10/3)PD, PPPDUCSISGPF definition15/24

Uzunoglu et al. [18]2012Germany, Italy, GreeceRCT2009–201164.865.257 (33/24)44 (29/15)PD, PPPDHSISGPF definition3/5

Heverhagen et al. [19]2012GermanyPNR2005–20116164.150 (37/13)50 (34/16)PPPDHSISGPF definition16/24

Yui et al. [20]2014JapanRetro.2000–2010666557 (31/26)52 (29/23)DPUSADUD group: ISGPF definition
CD group: ISGPF definition and other definitions that were not available
15/24

UD: ultrasonic dissection, CD: conventional dissection, M/F: male/female, RCT: randomized controlled trial, DP: distal pancreatectomy, CUSA: Cavitron Ultrasonic Surgical Aspirator, Retro.: retrospective observational study, HS: harmonic scalpel, PNR: prospective nonrandomized observational study, PD: pancreaticoduodenectomy, PPPD: pylorus-preserving PD, UCS: ultrasonically curved shear, ISGPF: International Study Group on Pancreatic Fistula, USAD: ultrasonically activated device.
Jadad score for RCTs and MINORS score for non-RCTs.