Ultrasonic Dissection versus Conventional Dissection for Pancreatic Surgery: A Meta-Analysis

Table 2

Summary of meta-analysis.

Outcome	Number of studies	Number of participants		Heterogeneity	Overall effect size	95% CI of overall effect	P
		UD	CD
UD versus CD for DP
Pancreatic fistula	3	95	103	, %	RR = 0.46	0.27–0.76	0.003
Abdominal abscess	3	95	103	, %	RR = 0.24	0.08–0.71	0.01
Postoperative hemorrhage	2	68	72	NA	RR = 0.58	0.03–13.22	0.73
Operation time (min)	1	57	52	NA	MD = −63.00	−116.41 to −9.59	0.02
Intraoperative blood loss (mL)	1	57	52	NA	MD = −215.00	−695.96 to 265.96	0.38
Hospital stay (days)	1	57	52	NA	MD = −9.00	−17.78 to −0.22	0.04
Mortality	3	95	103	NA	RR = 0.91	0.06–14.22	0.95
Morbidity	1	57	52	NA	RR = 0.81	0.55–1.20	0.30
UD versus CD for PD/PPPD
Pancreatic fistula	3	120	107	, %	RR = 0.79	0.48–1.29	0.34
Abdominal abscess	1	13	13	NA	RR = 0.33	0.01–7.50	0.49
Postoperative hemorrhage	2	70	57	NA	RR = 1.80	0.49–6.57	0.37
Operation time (min)	3	120	107	, %	MD = −5.98	−31.98 to 20.03	0.65
Intraoperative blood loss (mL)	3	120	107	, %	MD = −183.08	−346.01 to −20.16	0.03
Transfused blood unit	2	107	94	, %	MD = −0.69	−1.28 to −0.09	0.02
Hospital stay (days)	3	120	107	, %	MD = 1.04	−2.92 to 5.00	0.61
Mortality	3	120	107	, %	RR = 0.29	0.08–1.08	0.07
Morbidity	2	70	57	, %	RR = 1.00	0.72–1.38	0.99

CI: confidence interval, UD: ultrasonic dissection, CD: conventional dissection, RR: risk ratio, DP: distal pancreatectomy, PD: pancreaticoduodenectomy, PPPD: pylorus-preserving PD, NA: not applicable, MD: mean difference.