Clinical Risk Factors for Gastroduodenal Ulcer in Romanian Low-Dose Aspirin Consumers

Table 2

Results from univariate binary logistic regression.

Variables	Statistics		Crude OR	95% CI
Gender M versus F	2.29	0.001	4.11	1.72–9.85
Age (years)	0.50	0.472	1.01	0.98–1.05
Age ≥ 70 years		0.942	0.98	0.49–1.93
Anticoagulants	2.64	0.029	3.10	1.13–8.55
NSAIDs	2.54	0.013	3.56	1.31–9.68
Heart failure	2.53	0.007	4.22	1.47–12.09
Kidney disease	2.36	0.07	2.46	0.93–6.53
Respiratory disease	1.31	0.07	2.46	0.93–6.53
Liver disease	2.36	0.011	2.97	1.28–6.90
Cerebrovascular disease	3.48	0.004	6.48	1.83–22.90
Diabetes mellitus	2.63	0.043	2.52	1.03–6.15
H. pylori positive	1.58	0.202	1.71	0.75–3.89
Peptic ulcer history	2.36	0.044	2.34	1.02–5.37
Upper abdominal pain		0.342	0.67	0.30–1.52
Heartburn		0.615	0.78	0.29–2.07
Nausea/vomiting	1.26	0.192	1.92	0.72–5.12
Bloating	1.79	0.074	2.10	0.93–4.74
Smoking	0.86	0.237	2.40	0.56–10.23
Alcohol consumption	2.58	0.018	3.00	1.20–7.48

Crude values obtained from Wald’s test.
Response variable: presence of gastroduodenal ulcer in patients taking LDA.
OR: odds ratio.
CI: 95% confidence interval.
M: male, F: female.
Over 5 cigarettes/day.
More than 2 units/day, 1 unit: 10 mL pure alcohol.
NSAIDs: nonsteroidal anti-inflammatory drugs.