Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability

Table 1

Summary of inflammatory cytokines involved in gastrointestinal intestinal disorders.

Diseases	Species	Inflammatory cytokines	Reference
IBD	Human	TNF-α	Suenaert et al., 2002 [65]
			Järnerot et al., 2005 [66]
	Human	IFN-γ	Niessner and Volk, 1995 [67]
			Haep et al., 2015 [68]
			Rismo et al., 2012 [69]
	Human	IL-10	Niessner and Volk, 1995 [67]
	Human	IL-17A	Liu et al. 2016, [70]
			Rismo et al., 2012 [69]
	Human	IL-1β	Winchester and Pepine, 2015 [71]
	Human	IL-8	Rodríguez-Perlvárez  et al.,2012 [72]
	Human	IL-2	Zaidi et al., 2016 [73]
	Human	IL-13	Heller et al., 2005 [24]
Celiac disease	Human	IL-15	Koning [74]
	Human	IFN-γ	Schuppan et al., 2009 [75]
		IL-21	Schuppan et al., 2009 [75]
IBS	Human	IFN-γ	Barbaro et al., 2016 [76]
	Human	IL-10	Chen et al., 2012 [77]
	Human	TNF-α	Vivinus-Nébot et al., 2014 [78]
		IL-6	Seyedmirzaee et al., 2016 [79]
		Il-8	Seyedmirzaee et al., 2016 [79]
		IL-1β	Pike et al., 2015 [80]
FD	Human	TNF-α	Liebregts et al., 2011 [81]
		IL-10	Liebregts et al., 2011 [81]
		IL-1β	Liebregts et al., 2011 [81]