Corticotropin-Releasing Factor and Toll-Like Receptor Gene Expression Is Associated with Low-Grade Inflammation in Irritable Bowel Syndrome Patients with Depression

Figure 1

(a) IL-6 mRNA expression between DP-IBS, NDP-IBS, and the control group (, , and , resp., , ). IL-6 mRNA levels in DP-IBS and NDP-IBS patients were significantly higher than those in the control group. IL-6 mRNA levels in DP-IBS patients were significantly higher than that in NDP-IBS patients (). (b) IL-10 mRNA expressions in DP-IBS and NDP-IBS patients were significantly lower than those in the control group (, , and , resp., , and ). IL-10 mRNA level in DP-IBS is lower than NDP-IBS, but there was no statistical significance ().

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