Research Article

Corticotropin-Releasing Factor and Toll-Like Receptor Gene Expression Is Associated with Low-Grade Inflammation in Irritable Bowel Syndrome Patients with Depression

Figure 2

(a) CRF1 mRNA in DP-IBS, NDP-IBS, and control group (, , and , resp., , ). CRF1 mRNA expression levels in DP-IBS and NDP-IBS patients were significantly higher than those in the control group and in DP-IBS patients were significantly higher than in NDP-IBS patients (). (b) CRF2 mRNA expressions in DP-IBS, NDP-IBS, and control group (, , and , resp., , ). CRF2 mRNA levels in DP-IBS and NDP-IBS patients were significantly higher than those in the control group ().
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