Research Article

High Prevalence of Human Papillomavirus in Colorectal Cancer in Hispanics: A Case-Control Study

Table 2

Association between HPV infection status and CRC.

CharacteristicsCRC cases 

(%)
Controls 

(%)
valueOR (95% CI)

HPV infection status
 HPV (+)19 (42.2)1 (2.8)25.58 (3.22–203.49)
 HPV (−)26 (57.8)35 (97.2)Reference
HPV infection status per colorectal subsite
 Proximal
  HPV (+)4 (8.9)1 (2.8)0.00146.67 (3.71–1175.05)
  HPV (−)3 (6.7)35 (97.2)Reference
 Distal
  HPV (+)8 (17.8)1 (2.8)25.46 (3.32–582.87)
  HPV (−)11 (24.5)35 (97.2)Reference
 Rectum
  HPV (+)7 (15.6)1 (2.8)0.00220.42 (2.62–474.77)
  HPV (−)12 (26.7)35 (97.2)Reference

values were calculated using chi-square tests or Fisher’s exact tests, when appropriate. Mid- exact method; Fisher’s exact test.