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Gastroenterology Research and Practice
Volume 2016, Article ID 7897390, 7 pages
http://dx.doi.org/10.1155/2016/7897390
Clinical Study

Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association

1Department of Gastroenterology, Nassau University Medical Center, East Meadow, NY 11554, USA
2Department of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USA
3Research Department, NYIT College of Osteopathic Medicine, Glen Head, NY 11545, USA

Received 11 January 2016; Accepted 6 March 2016

Academic Editor: Per Hellström

Copyright © 2016 Albin Abraham et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Data examining the association between obesity and erosive esophagitis (ErE) have been inconsistent, with very little known about interracial variation. Goals. To examine the association between obesity and ErE among patients of different ethnic/racial backgrounds. Methods. The study sample included 2251 patients who underwent esophagogastroduodenoscopy (EGD). The effects of body mass index (BMI) on ErE were assessed by gender and in different ethnic groups. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariate logistic regression analysis. Results. The prevalence of ErE was 29.4% (661/2251). Overweight and obese subjects were significantly more likely to have ErE than individuals with a normal BMI, with the highest risk seen in the morbidly obese (OR 6.26; 95% CI 3.82–10.28; ). Normal weight Black patients were less likely to have ErE as compared to Caucasians (OR 0.46; 95% CI 0.27–0.79; ), while the odds ratio comparing normal weight Hispanics to normal weight Whites was not statistically significant. No effect modification was seen between BMI and race/ethnicity or BMI and gender. Significant trends were seen in each gender and ethnicity. Conclusions. The effect of BMI on ErE does not appear to vary by race/ethnicity or gender.