Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association
Table 1
Comparisons of patient characteristics based on endoscopic presence of erosive esophagitis.
Normal esophagus ()
Erosive esophagitis ()
OR (95% CI)
value
Gender
Females
1012 (63.65)
355 (53.71)
1
Males
578 (36.35)
306 (46.29)
1.51 (1.26–1.81)
<0.01
Age (mean ± SD)
52.64 ± 15.49
52.97 ± 14.37
0.61
Mean BMI kg/m2 (SD)
27.99 (8.57)
29.85 (6.45)
<0.01
Race
Whites
277 (17.42)
186 (28.14)
1
Chi-square <0.01
Blacks
445 (27.99)
148 (22.39)
0.49 (0.38–0.64)
<0.01
Hispanics
770 (48.43)
281 (42.51)
0.54 (0.43–0.68)
<0.01
Others
98 (6.16)
46 (6.96)
Alcohol use
Never use
1186 (76.96)
421 (66.83)
1
Former use
86 (5.58)
49 (7.78)
1.61 (1.11–2.32)
0.01
Current use
269 (17.46)
160 (25.4)
1.68 (1.34–2.10)
<0.01
Smoking
Never smoker
1196 (76.23)
440 (68.01)
1
Former smoker
140 (8.92)
70 (10.82)
1.36 (1.00)
0.05
Current smoker
233 (14.85)
137 (21.17)
1.60 (1.26–2.03)
0.01
Hiatal hernia
374 (23.54)
189 (28.59)
1.30 (1.06–1.60)
0.01
NSAID use
377 (23.73)
167 (25.26)
1.09 (0.88–1.34)
0.44
Acid suppression therapy
716 (45.09)
244 (36.91)
0.71 (0.59–0.86)
<0.01
Diabetes mellitus
273 (17.18)
110 (16.64)
0.96 (0.76–1.23)
0.76
H. pylori infection
436 (29.68)
126 (21.36)
0.64 (0.51–0.81)
<0.01
Peptic ulcer
274 (17.23)
128 (19.36)
1.15 (0.91–1.46)
0.23
Adjusted for age, race, sex, alcohol use, smoking, NSAID use, acid suppression therapy, presence of peptic ulcers, Helicobacter pylori (H. pylori) positivity on histopathological examination, and presence of hiatal hernia. Age documented at the time of the initial endoscopic intervention.
