Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association
Table 3
Joint effects of obesity and gender on erosive esophagitis.
Normal esophagus ()
Erosive esophagitis ()
OR (95% CI)
value
for trend
Normal weight female
332 (20.88)
64 (9.68)
1
In females
Overweight female
346 (21.76)
130 (19.67)
2.30 (1.63–3.26)
<0.01
Class I obesity female
220 (13.84)
96 (14.52)
2.75 (1.90–3.98)
<0.01
Class II obesity female
73 (4.59)
29 (4.39)
2.51 (1.49–4.22)
<0.01
Class III obesity female
41 (2.58)
36 (5.45)
5.50 (3.20–9.46)
<0.01
Normal weight male
237 (14.91)
57 (8.62)
1.06 (0.71–1.60)
0.76
In males
Overweight male
217 (13.65)
142 (21.48)
3.49 (2.45–4.96)
<0.01
Class I obesity male
78 (4.91)
72 (10.89)
4.90 (3.18–7.53)
<0.01
Class II obesity male
33 (2.08)
17 (2.57)
2.68 (1.38–5.17)
<0.01
Class III obesity male
13 (0.82)
18 (2.72)
8.24 (3.72–18.23)
<0.01
Overweight or obese Classes I-II female
639 (40.19)
255 (38.58)
2.48 (1.81–3.39)
<0.01
In females
Overweight or obese Class III female
41 (2.58)
36 (5.45)
5.50 (3.20–9.46)
<0.01
Overweight or obese Classes I-II male
328 (20.63)
231 (34.95)
3.74 (2.70–5.19)
<0.01
In males
Overweight or obese Class III male
13 (0.82)
18 (2.72)
8.24 (3.72–18.23)
<0.01
Overweight or obese Classes I–III female
680 (42.77)
291 (44.02)
2.66 (1.95–3.62)
<0.01
Overweight or obese Classes I–III male
341 (21.45)
249 (37.67)
3.87 (2.80–5.36)
<0.01
Reference category for all regression models in table. Adjusted for age, race, sex, alcohol use, smoking, NSAID use, acid suppression therapy, presence of peptic ulcers, Helicobacter pylori (H. pylori) positivity on histopathological examination, and presence of hiatal hernia.
