Clinical Study

Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association

Table 4

Joint effects of obesity and ethnicity/race on erosive esophagitis.

Normal esophagus
()
Erosive esophagitis
()
OR (95% CI) value for trend

Normal weight Whites129 (8.65)46 (7.48)1<0.01
Overweight or Classes I-II obese Whites136 (9.12)125 (20.33)3.01 (1.96–4.62)<0.01
Class III obesity Whites12 (0.80)15 (2.44)4.28 (1.82–10.08)<0.01
Normal weight Blacks178 (11.93)27 (4.39)0.46 (0.27–0.79)<0.01<0.01
Overweight or Classes I-II obese Blacks243 (16.29)101 (16.42)1.53 (1.00–2.35)0.05
Class III obesity Blacks24 (1.61)20 (3.25)3.30 (1.63–6.69)<0.01
Normal weight Hispanics222 (14.88)37 (6.02)0.66 (0.39–1.10)0.11<0.01
Overweight or Classes I-II Hispanics532 (35.66)227(36.91)1.83 (1.21–2.75)<0.01
Class III obesity Hispanics16 (1.07)17 (2.76)5.08 (2.30–11.23)<0.01

Blacks, Whites, and Hispanics included in analysis.
Adjusted for age, race, sex, alcohol use, smoking, NSAID use, acid suppression therapy, presence of peptic ulcers, Helicobacter pylori (H. pylori) positivity on histopathological examination, and presence of hiatal hernia.