Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association
Table 4
Joint effects of obesity and ethnicity/race on erosive esophagitis.
Normal esophagus ()
Erosive esophagitis ()
OR (95% CI)
value
for trend
Normal weight Whites
129 (8.65)
46 (7.48)
1
<0.01
Overweight or Classes I-II obese Whites
136 (9.12)
125 (20.33)
3.01 (1.96–4.62)
<0.01
Class III obesity Whites
12 (0.80)
15 (2.44)
4.28 (1.82–10.08)
<0.01
Normal weight Blacks
178 (11.93)
27 (4.39)
0.46 (0.27–0.79)
<0.01
<0.01
Overweight or Classes I-II obese Blacks
243 (16.29)
101 (16.42)
1.53 (1.00–2.35)
0.05
Class III obesity Blacks
24 (1.61)
20 (3.25)
3.30 (1.63–6.69)
<0.01
Normal weight Hispanics
222 (14.88)
37 (6.02)
0.66 (0.39–1.10)
0.11
<0.01
Overweight or Classes I-II Hispanics
532 (35.66)
227(36.91)
1.83 (1.21–2.75)
<0.01
Class III obesity Hispanics
16 (1.07)
17 (2.76)
5.08 (2.30–11.23)
<0.01
Blacks, Whites, and Hispanics included in analysis. Adjusted for age, race, sex, alcohol use, smoking, NSAID use, acid suppression therapy, presence of peptic ulcers, Helicobacter pylori (H. pylori) positivity on histopathological examination, and presence of hiatal hernia.