Elevated Circulating hsa-miR-106b, hsa-miR-26a, and hsa-miR-29b in Type 2 Diabetes Mellitus with Diarrhea-Predominant Irritable Bowel Syndrome

Figure 1

Clustering and principle component analysis of 35 miRNAs with significantly different expression values ( value 0.05; ). Unsupervised hierarchical clustering analysis of 35 miRNAs with significantly different expression values in T2DM with D-IBS (A), T2DM (B), and D-IBS (C) compared with the matched samples (D). One through three represent three different patients for each group. The color key under the heat map represents the different expression levels. Expression levels of miRNAs are shown in red (upregulated) and green (downregulated), with brighter shades indicating higher fold differences.