Research Article

Differential Impacts of Soybean and Fish Oils on Hepatocyte Lipid Droplet Accumulation and Endoplasmic Reticulum Stress in Primary Rabbit Hepatocytes

Figure 3

Soybean oils but not fish oils cause ER and mitochondrial damage. Primary hepatocytes were treated with 0.4% or 1% soybean (SO) or fish oil- (FO-) based lipid emulsions and the changes to both ER and mitochondrial morphologies were examined using TEM (×10000). (a) CON group, (b) FO High group, (c) FO Low group, (d) SO High group, and (e) SO Low group. White filled triangle indicates mitochondria; black filled arrow indicates ER; white filled arrow indicates lipid droplets. ER, endoplasmic reticulum; TEM, transmission electron microscopy.
(a)
(b)
(c)
(d)
(e)