Review Article

Pretreatment Lymphocyte Monocyte Ratio Predicts Long-Term Outcomes in Patients with Digestive System Tumor: A Meta-Analysis

Table 1

Main characteristics of eligible studies.

CharacteristicsNumber of studiesNumber of patients

All eligible studies2212829
Year of publication
 201431272
 2015132951
 201668606
Endpoint used
 OS1811610
 CSS61770
 DFS/RFS138338
Method to get UVA HR
 Reported1610853
 Estimated61976
Multivariate analysis
 Performed2112527
 Unperformed1302
Anatomic structure
 Gastrointestinal tract1711340
 Nongastrointestinal tract51489
Tumor site
 Esophagus3892
 Stomach31741
 Colorectal118707
 Liver2660
 Pancreas3829
Stage
 NMS119412
 Mixed31789
 MS81628
Ethnicity
 Asian1611285
 Non-Asian61544
Cut-off value
 <3.0109272
 ≥3.0123557
Treatment
 With surgery1812210
 No surgery4619

OS: overall survival; CSS: cancer-specific survival; DFS: disease-free survival; RFS: recurrence-free survival; UVA: univariate analysis; HR: hazard ratio; NMS: nonmetastatic stage; MS: metastatic stage.