Protective Effect of Daikenchuto on Dextran Sulfate Sodium-Induced Colitis in Mice

Figure 4

Histopathological analysis of hematoxylin and eosin-stained sections of the distal colon. (a, b) Untreated normal mouse: no disturbance of the ductal structure and no thickening of the wall. (c, d) Mouse provided with 5% dextran sulfate sodium (DSS) for 7 days: disturbance in the ductal structure and thickening of the wall (arrows). (e, f) Mouse administered a combination of 5% DSS and daikenchuto: disturbance in the ductal structure and thickening of the wall, but milder than that in mouse provided with DSS alone (arrows). Original magnification (a), (c), and (e): ×20; (b), (d), and (f): ×40.

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