Adjuvant Second-Dose Chemotherapy before Surgery for Patients with Locally Advanced Rectal Malignancy Is Not Beneficial: A Systematic Review and Meta-Analysis

<div>Forest plot for downstaging. A Mantel-Haenszel fixed-effects model was used for meta-analysis. Risk ratios are shown with 95% confidence interval.</div>

Gastroenterology Research and Practice

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Figure 3

Figure 3: Adjuvant Second-Dose Chemotherapy before Surgery for Patients with Locally Advanced Rectal Malignancy Is Not Beneficial: A Systematic Review and Meta-Analysis 

Figure 3 | Adjuvant Second-Dose Chemotherapy before Surgery for Patients with Locally Advanced Rectal Malignancy Is Not Beneficial: A Systematic Review and Meta-Analysis 