Review Article
Adjuvant Second-Dose Chemotherapy before Surgery for Patients with Locally Advanced Rectal Malignancy Is Not Beneficial: A Systematic Review and Meta-Analysis
Table 3
Risk of bias in the nonrandomized studies using modified Newcastle-Ottawa scale.
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Comparability variables: 1, age; 2, gender; 3, TN; 4, total mesorectal excision; 5, radial margin status; 6, distance from anal verge; 7, radiotherapy technique; 8, total dose of radiotherapy; and 9, adjuvant chemotherapy. If all characteristics were comparable, two stars; if >2 characteristics were comparable, one star; if <2 characteristics were comparable, no star. △The article provided the details of criteria for adequate random assignment. |