Impact of Body Mass Index on Surgical and Oncological Outcomes in Laparoscopic Total Mesorectal Excision for Locally Advanced Rectal Cancer after Neoadjuvant 5-Fluorouracil-Based Chemoradiotherapy
Table 2
Perioperative outcomes between nonobese and obese groups in locally advanced rectal cancer patients following nCRT.
Variables
BMI < 25 ()
BMI ≥ 25 ()
value
Operative time (min)
207.9 ± 43.9
224.3 ± 38.8
0.004
Estimated blood loss (ml)
63.2 ± 87.6
73.6 ± 59.1
0.265
Conversion
9 (3.6)
4 (6.3)
0.332
Surgical procedure
0.497
Sphincter-preserving surgery
222 (89.2)
58 (92.1)
Abdominoperineal resection
27 (10.8)
5 (7.9)
Diverting stoma
127 (51.0)
34 (54.0)
0.674
Postoperative hospital stay
9.0 ± 6.1
8.9 ± 6.7
0.900
Time to flatus (days)
1.9 ± 0.9
1.9 ± 0.7
0.751
Time to faeces (days)
3.1 ± 1.7
2.9 ± 1.5
0.412
Time to off bed activities (days)
1.9 ± 0.8
1.9 ± 0.9
0.829
Time to liquid diet (days)
1.9 ± 1.0
1.8 ± 0.9
0.297
Time to soft diet (days)
4.5 ± 2.2
4.3 ± 1.7
0.463
Overall morbidity
58 (23.3)
15 (23.8)
0.931
Postoperative complicationsa
Anastomotic leakage
13 (5.2)
4 (6.3)
0.724
Ileus
15 (6.0)
5 (7.9)
0.580
Wound infection
10 (4.0)
5 (7.9)
0.194
Sepsis
3 (1.2)
1 (1.6)
0.809
Acute urinary retention
5 (1.6)
2 (3.2)
0.576
Respiratory complications
10 (4.0)
4 (6.3)
0.424
Othersb
9 (3.6)
4 (6.3)
0.332
Reoperation
2 (0.8)
1 (1.6)
0.569
Grade of morbidity
Minor
46 (18.5)
17 (27.0)
0.133
Major
25 (10.0)
8 (12.5)
0.540
aSome patients experienced more than one complication. bIncluding cardiovascular events, cerebrovascular events, deep vein thrombosis, and chyle leakage. Data are expressed as number (%) or as median ± standard deviation, where appropriate. nCRT: neoadjuvant chemoradiotherapy.
