Extramural Venous Invasion as Prognostic Factor of Recurrence in Stage 1 and 2 Colon Cancer
Table 2
Patient characteristics.
EMVI
IMVI
No EMVI
Number of patients
10
3
171
Gender
Male
5
50%
0
0%
94
55%
Female
5
50%
3
100%
77
45%
Age
78
(56–85)
70
73
(66–80)
Charlson age index
5.5
(2.75–7.25)
5
5
(3–6)
T-stage
1
0
0%
0
0%
10
6%
2
0
0%
0
0%
33
19%
3
9
90%
3
100%
106
62%
4
1
10%
0
0%
22
13%
Differentiation
Poor
0
0%
0
0%
13
8%
Well
10
100%
3
100%
151
92%
Adjuvant treatment
0
0%
0
0%
8
5%
LVI/PNI
2
80%
0
0%
14
8%
Number of examined lymph nodes
8.5
(5.5–15.25)
19
13
(8–18)
Tumour location
Distal
6
60%
0
0%
77
45%
Proximal
4
40%
3
100%
86
50%
Synchronous
0
0%
0
0%
8
5%
Recurrence
3
30%
1
33%
24
14%
Overall survival
5.96
1.21–9.24
5.58
6.75
5.09–8.59
Cause of death
Alive
4
40%
0
0%
108
63%
Tumour
2
20%
1
33%
15
9%
Complication of treatment
0
0%
0
0%
6
4%
Other
3
30%
2
67%
31
18%
Unknown
1
10%
0
0%
11
6%
Median and interquartile range. No interquartile ranges were reported for the IMVI group due to the small number of patients. EMVI: extramural invasion; IMVI: intramural invasion; LVI/PNI: lymphovascular invasion/perineural invasion.