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Gastroenterology Research and Practice
Volume 2017, Article ID 1732571, 7 pages
Clinical Study

Which Factors Are Important for Successful Sentinel Node Navigation Surgery in Gastric Cancer Patients? Analysis from the SENORITA Prospective Multicenter Feasibility Quality Control Trial

1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
2Department of Surgery, Dongnam Institute of Radiological and Medical Sciences, Cancer Center, Busan, Republic of Korea
3Department of Surgery, Gyeongsang National University, Jinju, Republic of Korea
4Department of Surgery, Gyeongsang National University, Changwon, Republic of Korea
5Department of Surgery, Ajou University School of Medicine, Suwon, Republic of Korea
6Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea
7Department of Surgery, Soonchunhyang University College of Medicine, Bucheon, Republic of Korea
8Department of Surgery, Chonnam National University Hwasun Hospital, Hwasun, Republic of Korea
9Gastric Cancer Center, Kyungpook National University Medical Center, Daegu, Republic of Korea
10Gastric Cancer Branch, National Cancer Center, Goyang, Republic of Korea

Correspondence should be addressed to Jae Seok Min; moc.revan@ygoodm

Received 2 March 2017; Accepted 10 April 2017; Published 15 June 2017

Academic Editor: Werner A. Draaisma

Copyright © 2017 Ji Yeong An et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. We investigated the results of quality control study prior to phase III trial of sentinel lymph node navigation surgery (SNNS). Methods. Data were reviewed from 108 patients enrolled in the feasibility study of laparoscopic sentinel basin dissection (SBD) in gastric cancer. Seven steps contain tracer injection at submucosa (step 1) and at four sites (step 2) by intraoperative esophagogastroduodenoscopy (EGD), leakage of tracer (step 3), injection within 3 minutes (step 4), identification of at least one sentinel basin (SB) (step 5), evaluation of sentinel basin nodes (SBNs) by frozen biopsy (step 6), and identification of at least five SBNs at back table and frozen sections (step 7). Results. Failure in step 7 () was the most common followed by step 3 () and step 6 (). We did not find any differences of clinicopathological factors between success and failure group in steps 1~6. In step 7, body mass index (BMI) was only the significant factor. The success rate was 97.1% in patients with BMI  <  23 kg/m2 and 80.3% in those with BMI ≥ 23 kg/m2 (). Conclusions. Lower BMI group showed higher success rate in step 7. Surgeons doing SNNS should be cautious when evaluating sufficient number of SBN in obese patients.