Research Article

Utility of Endoscopic Examination in the Diagnosis of Acute Graft-versus-Host Disease in the Lower Gastrointestinal Tract

Table 1

Definition and the histological grading system for acute GI GVHD.

GradeHistological feature

ISingle-cell necrosis (apoptosis) noted on medium power
IIEvidence of epithelial damage by crypt/grandular abscesses, epithelial flattening, or glandular/crypt dilation
IIIDropout of one or more crypts/grands
IVTotal epithelial denudation