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Gastroenterology Research and Practice
Volume 2017, Article ID 2397430, 6 pages
Review Article

The Role of Endoscopic Ultrasound in the Diagnosis and Management of Primary Gastric Lymphoma

1First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece
2School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
3Department of Gastroenterology, Hygeia Hospital, Athens, Greece
4Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA
5Second Department of Propaedeutic Surgery, National and Kapodistrian University of Athens, Athens, Greece
6Hepatogastroenterology Unit, Second Department of Internal Medicine and Research Unit, “Attikon” University General Hospital and National and Kapodistrian University of Athens, Haidari, Greece

Correspondence should be addressed to Athanasios D. Sioulas; rg.oohay@saluoishta

Received 2 January 2017; Accepted 22 February 2017; Published 16 March 2017

Academic Editor: Alfred Gangl

Copyright © 2017 Dimitrios Schizas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Endoscopic ultrasound (EUS) is considered a valuable diagnostic tool during the workup of malignant gastric lesions, including primary gastric lymphomas (PGL). Although endoscopy combined with multiple biopsies remains essential in the establishment of PGL diagnosis, EUS utilization in locoregional disease staging has been well documented in the literature. Data also support the possible role of EUS in prediction of response to first-line treatment, that is, Helicobacter pylori eradication. However, its application in the posttreatment setting remains problematic, since concordance rates between endosonography and histology findings during follow-up seem to vary substantially. The aim of the present review is to summarize all available data regarding the role of EUS in the management of PGL.