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Gastroenterology Research and Practice
Volume 2017, Article ID 2795176, 7 pages
https://doi.org/10.1155/2017/2795176
Research Article

Bowel Ischemia in ICU Patients: Diagnostic Value of I-FABP Depends on the Interval to the Triggering Event

Department of General, Visceral and Vascular Surgery, Jena University Hospital, Jena, Germany

Correspondence should be addressed to Stefan Ludewig; ed.anej-inu.dem@giwedul.nafets

Received 2 February 2017; Accepted 9 April 2017; Published 28 May 2017

Academic Editor: Kazuhiko Uchiyama

Copyright © 2017 Stefan Ludewig et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. Sertaridou, V. Papaioannou, G. Kolios, and I. Pneumatikos, “Gut failure in critical care: old school versus new school,” Annals of Gastroenterology, vol. 28, no. 3, pp. 309–322, 2015. View at Google Scholar
  2. E. A. Deitch, “Gut-origin sepsis: evolution of a concept,” The Surgeon, vol. 10, no. 6, pp. 350–356, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Marston, “Responses of the splanchnic circulation to ischaemia,” Journal of Clinical Pathology. Supplement (Royal College of Pathologists), vol. 11, no. 30, pp. 59–67, 1977. View at Google Scholar
  4. M. Leone, C. Bechis, K. Baumstarck et al., “Outcome of acute mesenteric ischemia in the intensive care unit: a retrospective, multicenter study of 780 cases,” Intensive Care Medicine, vol. 41, no. 4, pp. 667–676, 2015. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Acosta, “Epidemiology of mesenteric vascular disease: clinical implications,” Seminars in Vascular Surgery, vol. 23, no. 1, pp. 4–8, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. P. H. van der Voort, B. Westra, J. P. Wester et al., “Can serum L-lactate, D-lactate, creatine kinase and I-FABP be used as diagnostic markers in critically ill patients suspected for bowel ischemia,” BMC Anesthesiology, vol. 14, no. 1, p. 111, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. N. J. Evennett, M. S. Petrov, A. Mittal, and J. A. Windsor, “Systematic review and pooled estimates for the diagnostic accuracy of serological markers for intestinal ischemia,” World Journal of Surgery, vol. 33, no. 7, pp. 1374–1383, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. M. M. Pelsers, Z. Namiot, W. Kisielewski et al., “Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility,” Clinical Biochemistry, vol. 36, no. 7, pp. 529–535, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. J. C. Sacchettini, L. J. Banaszak, and J. I. Gordon, “Expression of rat intestinal fatty acid binding protein in E. coli and its subsequent structural analysis: a model system for studying the molecular details of fatty acid-protein interaction,” Molecular and Cellular Biochemistry, vol. 98, no. 1-2, pp. 81–93, 1990. View at Google Scholar
  10. T. Kanda, A. Tsukahara, K. Ueki et al., “Diagnosis of ischemic small bowel disease by measurement of serum intestinal fatty acid-binding protein in patients with acute abdomen: a multicenter, observer-blinded validation study,” Journal of Gastroenterology, vol. 46, no. 4, pp. 492–500, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. J. M. Lieberman, J. Sacchettini, C. Marks, and W. H. Marks, “Human intestinal fatty acid binding protein: report of an assay with studies in normal volunteers and intestinal ischemia,” Surgery, vol. 121, no. 3, pp. 335–342, 1997. View at Publisher · View at Google Scholar · View at Scopus
  12. B. Relja, M. Szermutzky, D. Henrich et al., “Intestinal-FABP and liver-FABP: novel markers for severe abdominal injury,” Academic Emergency Medicine, vol. 17, no. 7, pp. 729–735, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. I. C. Vermeulen Windsant, F. A. Hellenthal, J. P. Derikx et al., “Circulating intestinal fatty acid-binding protein as an early marker of intestinal necrosis after aortic surgery: a prospective observational cohort study,” Annals of Surgery, vol. 255, no. 4, pp. 796–803, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. A. Camkıran, A. Dönmez, D. Aldemir, R. A. Işgüzar, and B. Gültekin, “Clinical significance of intestinal type fatty acid binding protein in patients undergoing coronary artery bypass surgery,” Anadolu Kardiyoloji Dergisi, vol. 11, no. 6, pp. 536–541, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. D. R. Cronk, T. P. Houseworth, D. G. Cuadrado, G. S. Herbert, M. N. PM, and K. S. Azarow, “Intestinal fatty acid binding protein (I-FABP) for the detection of strangulated mechanical small bowel obstruction,” Current Surgery, vol. 63, no. 5, pp. 322–325, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. J. H. Holmes, J. M. Lieberman, C. B. Probert et al., “Elevated intestinal fatty acid binding protein and gastrointestinal complications following cardiopulmonary bypass: a preliminary analysis,” The Journal of Surgical Research, vol. 100, no. 2, pp. 192–196, 2001. View at Publisher · View at Google Scholar · View at Scopus
  17. D. H. Schellekens, J. Grootjans, S. A. Dello et al., “Plasma intestinal fatty acid-binding protein levels correlate with morphologic epithelial intestinal damage in a human translational ischemia-reperfusion model,” Journal of Clinical Gastroenterology, vol. 48, no. 3, pp. 253–260, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. S. J. Hanssen, J. P. Derikx, I. C. Vermeulen Windsant et al., “Visceral injury and systemic inflammation in patients undergoing extracorporeal circulation during aortic surgery,” Annals of Surgery, vol. 248, no. 1, pp. 117–125, 2008. View at Publisher · View at Google Scholar · View at Scopus