Procalcitonin-Guided Antibiotics after Surgery for Peritonitis: A Randomized Controlled Study

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Indication</td><td class="align_center">Duration</td><td class="align_center">First choice antibiotics</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Perforated appendicitis with peritonitis</td><td class="align_center">5 days</td><td class="align_center">Amoxicillin/clavulanic acid<br/>Allergy: ciprofloxacin + metronidazole</td></tr><tr><td class="align_left">Peritonitis due to gastrointestinal perforation</td><td class="align_center">10 days</td><td class="align_center">Amoxicillin/clavulanic acid. If severe infection: imipenem or piperacillin/tazobactam<br/>Allergy: ciprofloxacin + metronidazole</td></tr><tr><td class="align_left">Peritonitis due to gastrointestinal perforation, acquired in-hospital</td><td class="align_center">10 days</td><td class="align_center">Imipenem or piperacillin/tazobactam<br/>Allergy: ciprofloxacin + metronidazole</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Institutional guidelines for duration of antibiotic therapy, based on the Surgical Infection Society guidelines [<a href="/journals/grp/2017/3457614/#B15">15</a>–<a href="/journals/grp/2017/3457614/#B17">17</a>].

Gastroenterology Research and Practice

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Table 1

Table 1: Procalcitonin-Guided Antibiotics after Surgery for Peritonitis: A Randomized Controlled Study 