Research Article

Serum Alanine Aminotransferase Levels within Normal Range Have Different Associations with Augmentation Index and Other Cardiometabolic Risk Factors in Nondrinkers and Drinkers: A Chinese Community-Based Analysis

Table 2

Characteristics of drinkers according to the quartiles of serum ALT levels.

CharacteristicsQuartile 1
≤10 U/L ()
Quartile 2
11–20 U/L ()
Quartile 3
21–30 U/L ()
Quartile 4
31–40 U/L ()
value

Age (year)44 (31–63)46 (34–58)45 (34–55)43 (35–53)0.109
Men (%)71 (77.2)540 (90.8)321 (94.7)140 (95.2)<0.001
BMI (kg/m2)23.57 (21.41–25.79)24.87 (22.95–26.85)25.85 (23.85–27.72)27.04 (25.46–29.00)<0.001
Hypertension (%)21 (22.8)192 (32.3)109 (32.2)52 (35.4)0.226
DM (%)4 (4.3)34 (5.7)20 (5.9)18 (12.2)0.023
SBP (mmHg)120 (113–130)125 (117–137)126 (116–136)126 (118–138)0.017
DBP (mmHg)74 (68–80)78 (71–83)80 (72–87)80 (72–88)<0.001
HR (beats/minute)74 (67–82)72 (66–79)74 (66–82)74 (68–82)0.049
Triglyceride (mmol/L)0.92 (0.73–1.26)1.25 (0.89–1.72)1.54 (1.09–2.23)1.72 (1.24–2.77)<0.001
HDL-c (mmol/L)1.53 (1.35–1.80)1.39 (1.19–1.59)1.32 (1.14–1.54)1.26 (1.03–1.50)<0.001
LDL-c (mmol/L)2.20 (1.85–2.80)2.54 (2.12–3.02)2.68 (2.27–3.10)2.76 (2.29–3.35)<0.001
FBG (mmol/L)4.87 (4.53–5.20)4.89 (4.59–5.19)4.98 (4.66–5.33)5.01 (4.68–5.52)0.002
AIx (%)70 (60–80)72 (62–83)71 (60–81)72 (61–82)0.470
Drinking dosage42 (34–57)95 (54–140)167 (80–279)257 (117–500)<0.001

ALT: alanine aminotransferase; BMI: body mass index; DM: diabetes mellitus; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; HDL-c: high-density lipoprotein-cholesterol; LDL-c: low-density lipoprotein-cholesterol; FBG: fasting blood glucose; AIx: augmentation index.