Modulation of Colorectal Cancer Risk by Polymorphisms in 51Gln/His, 64Ile/Val, and 148Asp/Glu of APEX Gene; 23Gly/Ala of XPA Gene; and 689Ser/Arg of ERCC4 Gene

Table 4

The distribution of genotypes and allele frequencies and the analysis of the odds ratio (OR) for 23Gly/Ala polymorphism of XPA gene in patients with colorectal cancer (CRC) and the control group.

Genotype/allele	Patients ()	Controls ()	OR (95% CI)
Gly/Gly	31	95	1 (ref)	—
Gly/Ala	263	150	5.373 (3.418–8.446)	<0.0001
Ala/Ala	16	59	0.831 (0.419–1.649)	0.597
Gly	325	340	1 (ref)	—
Ala	295	268	1.152 (0.920–1.442)	0.218

Genotype distribution in the Hardy-Weinberg equilibrium, χ² = 0.988.
Values set in italics denote statistical significance.