Modulation of Colorectal Cancer Risk by Polymorphisms in 51Gln/His, 64Ile/Val, and 148Asp/Glu of APEX Gene; 23Gly/Ala of XPA Gene; and 689Ser/Arg of ERCC4 Gene

Table 5

The distribution of genotypes and allele frequencies and the analysis of the odds ratio (OR) for 64Ile/Val polymorphism of APEX gene in patients with colorectal cancer (CRC) and the control group.

Genotype/allele	Patients ()	Controls ()	OR (95% CI)
Ile/Ile	93	78	1 (ref)	—
Ile/Val	148	159	0.781 (0.537–1.136)	0.195
Val/Val	66	67	0.826 (0.525–1.301)	0.409
Ile	334	315	1 (ref)	—
Val	280	293	0.901 (0.720–1.128)	0.365

Genotype distribution in the Hardy-Weinberg equilibrium, χ² = 0.408.