Modulation of Colorectal Cancer Risk by Polymorphisms in 51Gln/His, 64Ile/Val, and 148Asp/Glu of APEX Gene; 23Gly/Ala of XPA Gene; and 689Ser/Arg of ERCC4 Gene

Table 6

The distribution of genotypes and allele frequencies and the analysis of the odds ratio (OR) for 689Ser/Arg polymorphism of ERCC4 gene in patients with colorectal cancer (CRC) and the control group.

Genotype/allele	Patients ()	Controls ()	OR (95% CI)
Ser/Ser	93	101	1 (ref)	—
Ser/Arg	155	160	1.052 (0.736–1.505)	0.777
Arg/Arg	61	43	1.541 (0.952–2.493)	0.078
Ser	341	362	1 (ref)	—
Arg	277	246	1.195 (0.953–1.499)	0.123

Genotype distribution in the Hardy-Weinberg equilibrium, χ² = 0.107.