Research Article

Nomogram Prediction of Anastomotic Leakage and Determination of an Effective Surgical Strategy for Reducing Anastomotic Leakage after Laparoscopic Rectal Cancer Surgery

Table 1

Univariate analysis of risk factors for anastomotic leakage in patients treated with laparoscopic rectal cancer surgery without diverting stoma ().

VariablesNumber of anastomotic leakage/total patients (%)

Sex0.002
 Female12/272 (4.4)
 Male53/464 (11.4)
Age, yr0.999
 ≥7029/330 (8.8)
 <7036/406 (8.9)
BMI (kg/m2)0.839
 <2546/507 (9.1)
 ≥2519/229 (8.3)
ASA score<0.001
 114/280 (7.8)
 241/517 (7.9)
 310/39 (25.6)
AJCC stage0.163
 0-II33/439 (7.5)
 II/IV32/297 (10.8)
Maximum tumor size (cm)0.896
 <424/320 (7.5)
 ≥429/416 (7.0)
Location of tumor0.005
 Upper25/447 (5.6)
 Mid16/215 (7.4)
 Low12/74 (16.2)
Operative time (min)0.003
 <24037/624 (5.9)
 ≥24016/112 (14.3)
Transfusion<0.001
 No41/674 (6.1)
 Yes12/62 (19.4)
Neoadjuvant chemoradiation0.051
 No42/651 (6.5)
 Yes11/85 (12.9)
Number of linear stapler firing0.061
 <220/376 (5.3)
 ≥233/360 (9.2)

AJCC: American Joint Committee on Cancer; ASA: American Society of Anesthesiologists, BMI: body mass index.