Nomogram Prediction of Anastomotic Leakage and Determination of an Effective Surgical Strategy for Reducing Anastomotic Leakage after Laparoscopic Rectal Cancer Surgery
Table 1
Univariate analysis of risk factors for anastomotic leakage in patients treated with laparoscopic rectal cancer surgery without diverting stoma ().
Variables
Number of anastomotic leakage/total patients (%)
Sex
0.002
Female
12/272 (4.4)
Male
53/464 (11.4)
Age, yr
0.999
≥70
29/330 (8.8)
<70
36/406 (8.9)
BMI (kg/m2)
0.839
<25
46/507 (9.1)
≥25
19/229 (8.3)
ASA score
<0.001
1
14/280 (7.8)
2
41/517 (7.9)
3
10/39 (25.6)
AJCC stage
0.163
0-II
33/439 (7.5)
II/IV
32/297 (10.8)
Maximum tumor size (cm)
0.896
<4
24/320 (7.5)
≥4
29/416 (7.0)
Location of tumor
0.005
Upper
25/447 (5.6)
Mid
16/215 (7.4)
Low
12/74 (16.2)
Operative time (min)
0.003
<240
37/624 (5.9)
≥240
16/112 (14.3)
Transfusion
<0.001
No
41/674 (6.1)
Yes
12/62 (19.4)
Neoadjuvant chemoradiation
0.051
No
42/651 (6.5)
Yes
11/85 (12.9)
Number of linear stapler firing
0.061
<2
20/376 (5.3)
≥2
33/360 (9.2)
AJCC: American Joint Committee on Cancer; ASA: American Society of Anesthesiologists, BMI: body mass index.