T Helper Lymphocyte and Mast Cell Immunohistochemical Pattern in Nonceliac Gluten Sensitivity

Table 1

Main demographic and clinical features of patients with nonceliac gluten sensitivity (NCGS), celiac disease (CD), and normal controls. The χ² for trend was employed for statistical analysis.

	NCGS ()	CD ()	Negative controls ()	value
Female/male sex	17/3	12/4	8/8	0.02
Age	33.1 ± 14.4	33.2 ± 11.2	28.5 ± 11.1	0.49
DQ2/8 ( and %)	6 (30%)	16 (100%)	3 (18.8%)	0.72
Iron deficiency anemia ( and %)	4 (20%)	5 (31.2%)	0 (0%)	0.14
Allergy to alimentary antigens other than wheat ( and %)	2 (10%)	1 (6.2%)	1 (6.2%)	0.19
Autoimmune thyroiditis ( and %)	4 (20%)	4 (25%)	0 (0%)	0.12
Weight loss ( and %)	10 (50%)	10 (62.5%)	0 (0%)	0.004
Abdominal pain ( and %)	16 (80%)	12 (75%)	6 (37.5%)	0.01
Diarrhea ( and %)	11 (55%)	10 (62.5%)	3 (18.8%)	0.04
Weakness ( and %)	9 (45%)	5 (31.2%)	1 (6.2%)	0.01
Headache ( and %)	9 (45%)	2 (12.5%)	2 (12.5%)	0.02