Effect of Neoadjuvant Chemoradiotherapy on Locally Advanced Rectal Mucinous Adenocarcinoma: A Propensity Score-Matched Study
Table 2
Surgical and pathological outcomes between nCRT and surgery-alone groups.
Characteristics
nCRT ()
Surgery alone ()
P value
Operative time (min)
0.765
Estimated blood loss (mL)
0.631
Conversion rate
3 (6.2)
1 (2.1)
0.617
Surgical approach
0.837
Laparoscopy
22 (45.8)
21 (43.8)
Open
26 (54.2)
27 (56.2)
Surgical procedure
0.009
LAR
38 (79.2)
29 (60.4)
APR
6 (12.5)
18 (37.5)
Hartmann’s procedure
4 (8.3)
1 (2.1)
Sphincter preservation
38 (79.2)
29 (60.4)
0.045
Temporary diverting ileostomy
25 (52.1)
11 (22.9)
0.003
Length of resection margin (cm)
Proximal
0.461
Distal
0.612
Number of lymph nodes retrieved
0.001
Number of positive lymph nodes
0.046
Resection margin involvement
Distal
0
1 (2.1)
NA
CRM (≤1.0 mm)
1 (2.1)
5 (10.4)
0.204
Neural or lymphovascular invasion
4 (8.3)
6 (12.5)
0.740
pTNM stage
< 0.001
0
2 (4.2)
0
I
7 (14.6)
0
II
15 (31.2)
3 (6.2)
III
24 (50.0)
45 (93.8)
Rectal cancer regression grade
1
15 (31.3)
NA
NA
2
20 (41.6)
NA
NA
3
13 (27.1)
NA
NA
Tumor downstaging
21 (43.8)
NA
NA
Nodal downstaging
24 (50.0)
NA
NA
Pathological complete response
2 (4.1)
NA
NA
Fisher’s exact test. Data are expressed as (%) or as median ± standard deviation, where appropriate. Row percents are presented. Significant differences are in bold. nCRT: neoadjuvant chemoradiotherapy; LAR: low anterior resection; APR: abdominoperineal resection; NA: not applicable; CRM: circumferential resection margin.
