Prognostic Value of Metastatic Tumoral Caveolin-1 Expression in Patients with Resected Gastric Cancer
Table 6
Univariate and multivariate analyses of cancer-specific survival rates using the Cox proportional hazards model in patients with metastatic lymph nodes.
Characteristics
Univariate analysis
Multivariate analysis
Hazard ratio
95% CI
value
Hazard ratio
95% CI
value
Age (>60 versus ≤60 years)
1.723
0.901–3.300
0.100
2.248
1.023–4.937
0.437
Sex (female versus male)
1.524
0.751–3.091
0.243
Advanced T stage (pT4 versus pT2-3)
3.318
1.018–10.816
0.047
3.905
1.173–12.992
0.026
Advanced N stage (pN2-3 versus pN1)
2.379
1.041–5.436
0.040
2.100
0.635–8.025
0.252
Lauren classification (diffuse versus nondiffuse)
1.291
0.669–2.491
0.446
Lymphatic invasion (yes versus no)
2.352
0.322–17.163
0.399
Venous invasion (yes versus no)
2.233
0.923–5.399
0.075
1.848
0.709–4.818
0.208
Tumor grade (moderate–poor versus well)
1.083
0.260–4.505
0.913
Adjuvant chemotherapy (yes versus no)
0.487
0.255–0.932
0.030
3.905
1.173–12.992
0.032
LNR (>median versus ≤median)
4.911
1.505–16.03
0.008
3.451
1.026–11.606
0.045
Tumoral Cav-1 expression, primary tumor (high versus low)
0.509
0.122–2.116
0.353
0.328
0.071–1.512
0.152
Stromal Cav-1 expression, primary tumor (high versus low)
1.324
0.652–2.687
0.437
Tumoral Cav-1 expression, lymph node (high versus low)
