Table of Contents Author Guidelines Submit a Manuscript
Gastroenterology Research and Practice
Volume 2017 (2017), Article ID 6126707, 9 pages
https://doi.org/10.1155/2017/6126707
Research Article

Outcome and Genetic Factors in IgG4-Associated Autoimmune Pancreatitis and Cholangitis: A Single Center Experience

1Department of Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany
2Division of Transplantation Immunology and Mucosal Biology, King’s College London, London, UK
3Institute of Transfusion Medicine, University Hospital Essen, Essen, Germany
4Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany

Correspondence should be addressed to Alisan Kahraman

Received 16 November 2016; Revised 19 January 2017; Accepted 29 January 2017; Published 2 March 2017

Academic Editor: Riccardo Casadei

Copyright © 2017 Matthias Buechter et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. L. Finkelberg, D. Sahani, V. Deshpande, and W. R. Brugge, “Autoimmune pancreatitis,” The New England Journal of Medicine, vol. 355, no. 25, pp. 2670–2676, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. R. K. Pearson, D. S. Longnecker, S. T. Chari et al., “Controversies in clinical pancreatology: autoimmune pancreatitis: does it exist?” Pancreas, vol. 27, no. 1, pp. 1–13, 2003. View at Google Scholar
  3. S. Fritz, F. Bergmann, L. Grenacher et al., “Diagnosis and treatment of autoimmune pancreatitis types 1 and 2,” The British Journal of Surgery, vol. 101, no. 10, pp. 1257–1265, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. K.-P. Kim, M.-H. Kim, M. H. Song, S. S. Lee, D. W. Seo, and S. K. Lee, “Autoimmune chronic pancreatitis,” The American Journal of Gastroenterology, vol. 99, no. 8, pp. 1605–1616, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. P. A. Hart, T. Kamisawa, W. R. Brugge et al., “Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis,” Gut, vol. 62, no. 12, pp. 1771–1776, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Buechter, C. G. Klein, C. Kloeters et al., “Tacrolimus as a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis,” Zeitschrift für Gastroenterologie, vol. 52, no. 6, pp. 564–568, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Shimosegawa, S. T. Chari, L. Frulloni et al., “International consensus diagnostic criteria for autoimmune pancreatitis: guidelines of the International Association of Pancreatology,” Pancreas, vol. 40, no. 3, pp. 352–358, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. R. P. Sah, S. T. Chari, R. Pannala et al., “Differences in clinical profile and relapse rate of type 1 versus type 2 autoimmune pancreatitis,” Gastroenterology, vol. 139, no. 1, pp. 140–148, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. T. Kamisawa, S. T. Chari, S. A. Giday et al., “Clinical profile of autoimmune pancreatitis and its histological subtypes: an international multicenter survey,” Pancreas, vol. 40, no. 6, pp. 809–814, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. P. A. Hart, M. J. Levy, T. C. Smyrk et al., “Clinical profiles and outcomes in idiopathic duct-centric chronic pancreatitis (type 2 autoimmune pancreatitis): the Mayo Clinic experience,” Gut, vol. 65, no. 10, pp. 1702–1709, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. R. Talar-Wojnarowska, A. Gąsiorowska, M. Olakowski et al., “Utility of serum IgG, IgG4 and carbonic anhydrase II antibodies in distinguishing autoimmune pancreatitis from pancreatic cancer and chronic pancreatitis,” Advances in Medical Sciences, vol. 59, no. 2, pp. 288–292, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Buechter, C. G. Klein, C. Kloeters, G. Gerken, A. Canbay, and A. Kahraman, “Diagnostic dilemma in a patient with jaundice: how to differentiate between autoimmune pancreatitis, primary sclerosing cholangitis and pancreas carcinoma,” Case Reports in Gastroenterology, vol. 6, no. 1, pp. 211–216, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Detlefsen, A. Mohr Drewes, M. Vyberg, and G. Klöppel, “Diagnosis of autoimmune pancreatitis by core needle biopsy: application of six microscopic criteria,” Virchows Archiv, vol. 454, no. 5, pp. 531–539, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. T. Kamisawa, M.-H. Kim, W.-C. Liao et al., “Clinical characteristics of 327 Asian patients with autoimmune pancreatitis based on Asian diagnostic criteria,” Pancreas, vol. 40, no. 2, pp. 200–205, 2011. View at Google Scholar
  15. F. Maire, Y. Le Baleur, V. Rebours et al., “Outcome of patients with type 1 or 2 autoimmune pancreatitis,” The American Journal of Gastroenterology, vol. 106, no. 1, pp. 151–156, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. H. Ohara, K. Okazaki, H. Tsubouchi et al., “Clinical diagnostic criteria of IgG4-related sclerosing cholangitis 2012,” Journal of Hepato-Biliary-Pancreatic Sciences, vol. 19, no. 5, pp. 536–542, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Maiers, L. Gragert, A. Madbouly et al., “16(th) IHIW: global analysis of registry HLA haplotypes from 20 million individuals: report from the IHIW registry diversity group,” International Journal of Immunogenetics, vol. 40, no. 1, pp. 66–71, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Detlefsen, G. Zamboni, L. Frulloni et al., “Clinical features and relapse rates after surgery in type 1 autoimmune pancreatitis differ from type 2: a study of 114 surgically treated European patients,” Pancreatology, vol. 12, no. 3, pp. 276–283, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Buijs, D. L. Cahen, M. J. van Heerde et al., “The long-term impact of autoimmune pancreatitis on pancreatic function, quality of life, and life expectancy,” Pancreas, vol. 44, no. 7, pp. 1065–1071, 2015. View at Publisher · View at Google Scholar
  20. S. Rasch, V. Phillip, R. M. Schmid, and H. Algül, “Epidemiology, clinical presentation, diagnosis and treatment of autoimmune pancreatitis: a retrospective analysis of 53 patients,” Pancreatology, vol. 16, no. 1, pp. 73–77, 2016. View at Publisher · View at Google Scholar · View at Scopus
  21. A. López-Serrano, J. Crespo, I. Pascual et al., “Diagnosis, treatment and long-term outcomes of autoimmune pancreatitis in Spain based on the international consensus diagnostic criteria: a multi-centre study,” Pancreatology, vol. 16, no. 3, pp. 382–390, 2016. View at Publisher · View at Google Scholar · View at Scopus
  22. T. Ikeura, R. Manfredi, G. Zamboni et al., “Application of international consensus diagnostic criteria to an Italian series of autoimmune pancreatitis,” United European Gastroenterology Journal, vol. 1, no. 4, pp. 276–284, 2013. View at Publisher · View at Google Scholar
  23. N. I. Church, S. P. Pereira, M. G. Deheragoda et al., “Autoimmune pancreatitis: clinical and radiological features and objective response to steroid therapy in a UK series,” The American Journal of Gastroenterology, vol. 102, no. 11, pp. 2417–2425, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. S. T. Chari, G. Kloeppel, L. Zhang et al., “Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document,” Pancreas, vol. 39, no. 5, pp. 549–554, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. T. Kamisawa, K. Takuma, N. Egawa, K. Tsuruta, and T. Sasaki, “Autoimmune pancreatitis and IgG4-related sclerosing disease,” Nature Reviews. Gastroenterology & Hepatology, vol. 7, no. 7, pp. 401–409, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. T. Ito, I. Nishimori, N. Inoue et al., “Treatment for autoimmune pancreatitis: consensus on the treatment for patients with autoimmune pancreatitis in Japan,” Journal of Gastroenterology, vol. 42, Supplement 18, pp. 50–58, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. T. Kamisawa, T. Shimosegawa, K. Okazaki et al., “Standard steroid treatment for autoimmune pancreatitis,” Gut, vol. 58, no. 11, pp. 1504–1507, 2009. View at Publisher · View at Google Scholar · View at Scopus
  28. T. Kamisawa, K. Okazaki, S. Kawa, T. Shimosegawa, M. Tanaka, and Research Committee for Intractable Pancreatic Disease and Japan Pancreas Society, “Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP,” Journal of Gastroenterology, vol. 45, no. 5, pp. 471–477, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. T. Kamisawa, K. Okazaki, S. Kawa et al., “Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 III. Treatment and prognosis of autoimmune pancreatitis,” Journal of Gastroenterology, vol. 49, no. 6, pp. 961–970, 2014. View at Publisher · View at Google Scholar · View at Scopus
  30. T. Tomiyama, K. Uchida, M. Matsushita et al., “Comparison of steroid pulse therapy and conventional oral steroid therapy as initial treatment for autoimmune pancreatitis,” Journal of Gastroenterology, vol. 46, no. 5, pp. 696–704, 2011. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Ghazale, S. T. Chari, L. Zhang et al., “Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy,” Gastroenterology, vol. 134, no. 3, pp. 706–715, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. K. Takuma, T. Kamisawa, T. Tabata, Y. Inaba, N. Egawa, and Y. Igarashi, “Short-term and long-term outcomes of autoimmune pancreatitis,” European Journal of Gastroenterology & Hepatology, vol. 23, no. 2, pp. 146–152, 2011. View at Google Scholar
  33. M. Sugimoto, T. Takagi, R. Suzuki et al., “Efficacy of steroid pulse therapy for autoimmune pancreatitis type 1: a retrospective study,” PLoS one, vol. 10, no. 9, article e0138604, 2015. View at Publisher · View at Google Scholar · View at Scopus
  34. Q. Meng, L. Xin, W. Liu et al., “Diagnosis and treatment of autoimmune pancreatitis in China: a systematic review,” PLoS One, vol. 10, no. 6, article e0130466, 2015. View at Publisher · View at Google Scholar · View at Scopus
  35. K. Okazaki and K. Uchida, “Autoimmune pancreatitis: the past, present, and future,” Pancreas, vol. 44, no. 7, pp. 1006–1016, 2015. View at Publisher · View at Google Scholar
  36. P. A. Hart, M. D. Topazian, T. E. Witzig et al., “Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience,” Gut, vol. 62, no. 11, pp. 1607–1615, 2013. View at Publisher · View at Google Scholar · View at Scopus
  37. S. Chatterjee, K. W. Oppong, J. S. Scott et al., “Autoimmune pancreatitis—diagnosis, management and long-term follow-up,” Journal of Gastrointestinal and Liver Diseases, vol. 23, no. 2, pp. 179–185, 2014. View at Google Scholar
  38. L. Xin, Y.-X. He, X.-F. Zhu et al., “Diagnosis and treatment of autoimmune pancreatitis: experience with 100 patients,” Hepatobiliary & Pancreatic Diseases International, vol. 13, no. 6, pp. 642–648, 2014. View at Google Scholar
  39. T. Wakabayashi, Y. Kawaura, Y. Satomura, H. Watanabe, Y. Motoo, and N. Sawabu, “Long-term prognosis of duct-narrowing chronic pancreatitis: strategy for steroid treatment,” Pancreas, vol. 30, no. 1, pp. 31–39, 2005. View at Google Scholar
  40. K. Hirano, M. Tada, H. Isayama et al., “Outcome of long-term maintenance steroid therapy cessation in patients with autoimmune pancreatitis: a prospective study,” Journal of Clinical Gastroenterology, vol. 50, no. 4, pp. 331–337, 2016. View at Publisher · View at Google Scholar · View at Scopus
  41. J. H. Stone, “IgG4-related disease: nomenclature, clinical features, and treatment,” Seminars in Diagnostic Pathology, vol. 29, no. 4, pp. 177–190, 2012. View at Publisher · View at Google Scholar · View at Scopus
  42. I. Naitoh, T. Nakazawa, H. Ohara et al., “Autoimmune pancreatitis associated with various extrapancreatic lesions during a long-term clinical course successfully treated with azathioprine and corticosteroid maintenance therapy,” Internal Medicine, vol. 48, no. 23, pp. 2003–2007, 2009. View at Google Scholar
  43. J. Mueller, A. Schmidt, G. Herrmann, and K. Caca, “Rituximab therapy for relapsing IgG4-autoimmune pancreatitis and cholangitis—a case report,” Zeitschrift für Gastroenterologie, vol. 53, no. 1, pp. 40–42, 2015. View at Publisher · View at Google Scholar · View at Scopus
  44. K. Hirano, M. Tada, H. Isayama et al., “Long-term prognosis of autoimmune pancreatitis with and without corticosteroid treatment,” Gut, vol. 56, no. 12, pp. 1719–1724, 2007. View at Publisher · View at Google Scholar · View at Scopus
  45. K. Kubota, S. Watanabe, T. Uchiyama et al., “Factors predictive of relapse and spontaneous remission of autoimmune pancreatitis patients treated/not treated with corticosteroids,” Journal of Gastroenterology, vol. 46, no. 6, pp. 834–842, 2011. View at Publisher · View at Google Scholar · View at Scopus
  46. K. Kubota, H. Iida, T. Fujisawa et al., “Clinical factors predictive of spontaneous remission or relapse in cases of autoimmune pancreatitis,” Gastrointestinal Endoscopy, vol. 66, no. 6, pp. 1142–1151, 2007. View at Publisher · View at Google Scholar · View at Scopus
  47. T. Kamisawa, A. Okamoto, T. Wakabayashi, H. Watanabe, and N. Sawabu, “Appropriate steroid therapy for autoimmune pancreatitis based on long-term outcome,” Scandinavian Journal of Gastroenterology, vol. 43, no. 5, pp. 609–613, 2008. View at Publisher · View at Google Scholar · View at Scopus
  48. K. Shimizu, J. Tahara, Y. Takayama et al., “Assessment of the rate of decrease in serum IgG4 level of autoimmune pancreatitis patients in response to initial steroid therapy as a predictor of subsequent relapse,” Pancreas, vol. 45, no. 6, pp. 1341–1346, 2016. View at Publisher · View at Google Scholar · View at Scopus
  49. R. Gupta, A. Khosroshahi, S. Shinagare et al., “Does autoimmune pancreatitis increase the risk of pancreatic carcinoma?: a retrospective analysis of pancreatic resections,” Pancreas, vol. 42, no. 3, pp. 506–510, 2013. View at Publisher · View at Google Scholar · View at Scopus
  50. X. Zhang, X. Liu, L. Joseph, L. Zhao, J. Hart, and S. Y. Xiao, “Pancreatic ductal adenocarcinoma with autoimmune pancreatitis-like histologic and immunohistochemical features,” Human Pathology, vol. 45, no. 3, pp. 621–627, 2014. View at Publisher · View at Google Scholar · View at Scopus
  51. J. Asano, T. Watanabe, T. Oguchi et al., “Association between immunoglobulin G4-related disease and malignancy within 12 years after diagnosis: an analysis after long-term follow-up,” The Journal of Rheumatology, vol. 42, no. 11, pp. 2135–2142, 2015. View at Publisher · View at Google Scholar · View at Scopus