A Review of the Role of Neurotensin and Its Receptors in Colorectal Cancer

Figure 1

Neurotensin signalling in colorectal cancer cells. NTS: neurotensin, NTSR1: neurotensin receptor 1, PLC: protein lipase C, PKC: protein kinase C, MAPK: mitogen-activated protein kinase, GSK-3: glycogen synthase kinase-3, DAG: diacylglycerol, PIP2: phosphatidylinositol 4,5-bisphosphate, IP3: inositol trisphosphate, ER: endoplasmic reticulum, EGFR: epidermal growth factor receptor, APC: adenomatous polyposis coli.