Association between HLA-DQ Gene Polymorphisms and HBV-Related Hepatocellular Carcinoma

Table 1

Characteristics of the studies included in the meta-analysis.

First author	Year	Ethnicity	Genotyping method	Polymorphisms	Number of HCC	Number of CHB	Number of controls	HCC			CHB			Control			PHWE
								GG	AG	AA	GG	AG	AA	GG	AG	AA
Hu [13]	2012	Chinese	TaqMan	rs2856718	1287	1334	1335	229	551	507	240	674	420	331	660	344	0.684
Chen [14]	2013	Chinese	TaqMan	rs9275572	506	772	—	319	170	17	445	277	50	—	—	—	0.438
Al-Qahtani [16]	2014	Saudi	DNA sequencing	rs2856718	71	603	505	18	31	22	184	173	246	155	223	127	0.010
		Arabian	TaqMan	rs9275572	81	208	571	39	34	8	88	95	25	223	251	97	0.069
Hou [17]	2015	Chinese	TaqMan	rs9275572	43	148	316	33	9	1	105	35	8	206	96	14	0.515
Gao [18]	2016	Chinese	Flight mass spectrometry	rs2856718	308	217	507	36	126	146	33	96	88	119	225	163	0.017
				rs9275572	308	396	505	212	84	12	245	129	22	249	196	60	0.029
Liu [19]	2016	Chinese	Flight mass spectrometry	rs2856718	154	112	254	19	62	73	17	50	45	61	112	81	0.073
				rs9275572	154	396	254	105	43	6	245	129	22	125	99	30	0.135