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Gastroenterology Research and Practice
Volume 2017, Article ID 7468728, 7 pages
Review Article

Polyethylene Glycol for Small Bowel Capsule Endoscopy

1Department of Gastroenterology, Xinqiao Hospital of Third Military Medical University, Chongqing 400037, China
2Department of Anesthesiology, West China Hospital, Chengdu, Sichuan 610041, China
3Department of Gastroenterology, West China Hospital, Chengdu, Sichuan 610041, China

Correspondence should be addressed to Jinlin Yang; moc.361@775-esuom

Received 19 September 2017; Accepted 28 November 2017; Published 27 December 2017

Academic Editor: Philipp Lenz

Copyright © 2017 Li Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Capsule endoscopy has been the first-line examination for small bowel diseases, yet its diagnostic yield is restricted by unsatisfactory bowel preparation. To evaluate the clinical effectiveness of different dosages of polyethylene glycol in patients undergoing capsule endoscopy, we performed a comprehensive meta-analysis of all randomized controlled trials involving polyethylene glycol in preparation for capsule endoscopy. The methodological quality of the trials was evaluated using the Cochrane Risk of Bias assessment instrument. In this study, 12 RCTs involving 2072 patients were included in this review. Our review indicated that 4 L and 2 L polyethylene (PEG) before capsule endoscopy (CE) and 500 mL PEG after CE increase the small bowel image quality, whereas 1 L PEG did not improve the small bowel image quality. PEG accelerated the gastric emptying time. There was no significant difference between the PEG group and control group in small bowel transit time, completion rates, and diagnostic yield.