Genetic Background and Clinical Characters of Pediatric Chronic Pancreatitis: Data and Implications from the East

Table 2

Genetic characteristics of patients with idiopathic chronic pancreatitis and controls.

	Pediatric ICP patients ()	Adult ICP patients (%) ()	Healthy controls (%) ()
PRSS1 c.365G>A	14/73 (19.18%^#)	12/100 (12.00%)	0 (0%)
CFTR c.2562T>G	2/73 (2.74%)	2/100 (2.00%)	0 (0%)
SPINK1 c.101A>G	0/73 (0%)	0/100 (0.00%)	0 (0%)
c.194+2T>C	41/73 (56.16%)	42/100 (42.00%)	0 (0%)

ICP: idiopathic chronic pancreatitis; PRSS1, protease serine 1; CFTR, cystic fibrosis transmembrane conductance regulator; SPINK1: serine protease inhibitor Kazal type 1; ^#the percentage refers to the proportion of patients within each group. juvenile ICP versus adult ICP.