Research Article
Genetic Background and Clinical Characters of Pediatric Chronic Pancreatitis: Data and Implications from the East
Table 3
Comparison of juvenile ICP patients with or without the SPINK1 c.194+2T>C mutations.
| | Juvenile patients carrying the mutation () | Juvenile patients without the mutation () | value |
| Age at onset (years, mean ± SD) | 10.22 ± 2.91 | 10.56 ± 4.02 | 0.674 | Female | 19 (46.3%) | 20 (65.2) | 0.170 | Clinical features | Type of pain attack | | | <0.001 | RAP | 29 (70.7%) | 10 (31.3%) | | RP | 6 (14.6%) | 2 (6.3%) | | RAP/P | 1 (2.4%) | 11 (34.4%) | | CPP | 3 (7.3%) | 8 (25.0%) | | No pain attack | 2 (4.9%) | 1 (3.1%) | | Jaundice | 1 (2.4%) | 0 (0.0%) | 0.307 | Pancreatic calcification | 32 (78.0%) | 26 (81.3%) | 0.737 | Complications | Pseudocyst | 4 (9.8%) | 3 (9.4%) | 0.956 | Diabetes mellitus | 4 (9.8%) | 0 (0%) | 0.069 | Steatorrhea | 0 (0.00%) | 0 (0.00%) | na |
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SPINK1, serine protease inhibitor Kazal type 1; SD, standard deviation; RAP, recurrent acute pancreatitis; RP, recurrent abdominal pain; RAP/P, recurrent acute pancreatitis or abdominal pain without significant increasing in serum amylase; CPP, chronic pancreatic pain.
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