Clinical Study
Baseline Renal Function Predicts Hyponatremia in Liver Cirrhosis Patients Treated with Terlipressin for Variceal Bleeding
Table 4
Univariate and multivariate logistic analyses of the risk factors for the in-hospital mortality.
| | Univariate analysis | Multivariate analysis | OR | 95% CI | value | OR | 95% CI | value |
| Hepatitis B virus positivity | 2.27 | 1.30–3.97 | 0.031 | 0.38 | 0.14–1.08 | 0.069 | Alcohol | 0.50 | 0.29–0.87 | 0.014 | 0.45 | 0.19–1.08 | 0.075 | Hepatocellular carcinoma | 3.43 | 1.92–6.14 | <0.001 | 8.39 | 2.81–25.05 | <0.001 | Hepatic encephalopathy | 3.64 | 1.99–6.66 | <0.001 | 1.61 | 0.69–3.78 | 0.273 | Bilirubin | 1.14 | 1.09–1.20 | <0.001 | 1.08 | 1.01–1.15 | 0.017 | Albumin | 0.32 | 0.18–0.54 | <0.001 | 0.95 | 0.42–2.17 | 0.907 | INR | 3.02 | 2.00–4.55 | <0.001 | 1.64 | 0.94–2.89 | 0.08 | Creatinine | 1.83 | 1.37–2.44 | <0.001 | 1.18 | 0.90–1.55 | 0.229 | Initial sodium | 0.90 | 0.86–0.94 | <0.001 | 0.97 | 0.91–1.02 | 0.248 | MELD score | 1.15 | 1.11–1.20 | <0.001 | | | | Child-Pugh score | 1.55 | 1.36–1.76 | <0.001 | | | | Development of hyponatremia | 0.13 | 0.05–0.32 | <0.001 | 0.19 | 0.07–0.61 | 0.005 | Shock on admission | 5.66 | 2.92–10.95 | <0.001 | 1.06 | 0.94–1.20 | 0.369 | Blood transfusion (PRCs) | 1.10 | 1.01–1.19 | 0.028 | 1.06 | 0.94–1.19 | 0.369 |
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INR: international normalized ratio; MELD: Model for End-Stage Liver Disease. PRCs: packed red cells.
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