Baseline Renal Function Predicts Hyponatremia in Liver Cirrhosis Patients Treated with Terlipressin for Variceal Bleeding

Table 4

Univariate and multivariate logistic analyses of the risk factors for the in-hospital mortality.

	Univariate analysis			Multivariate analysis
	OR	95% CI	value	OR	95% CI	value
Hepatitis B virus positivity	2.27	1.30–3.97	0.031	0.38	0.14–1.08	0.069
Alcohol	0.50	0.29–0.87	0.014	0.45	0.19–1.08	0.075
Hepatocellular carcinoma	3.43	1.92–6.14	<0.001	8.39	2.81–25.05	<0.001
Hepatic encephalopathy	3.64	1.99–6.66	<0.001	1.61	0.69–3.78	0.273
Bilirubin	1.14	1.09–1.20	<0.001	1.08	1.01–1.15	0.017
Albumin	0.32	0.18–0.54	<0.001	0.95	0.42–2.17	0.907
INR	3.02	2.00–4.55	<0.001	1.64	0.94–2.89	0.08
Creatinine	1.83	1.37–2.44	<0.001	1.18	0.90–1.55	0.229
Initial sodium	0.90	0.86–0.94	<0.001	0.97	0.91–1.02	0.248
MELD score	1.15	1.11–1.20	<0.001
Child-Pugh score	1.55	1.36–1.76	<0.001
Development of hyponatremia	0.13	0.05–0.32	<0.001	0.19	0.07–0.61	0.005
Shock on admission	5.66	2.92–10.95	<0.001	1.06	0.94–1.20	0.369
Blood transfusion (PRCs)	1.10	1.01–1.19	0.028	1.06	0.94–1.19	0.369

INR: international normalized ratio; MELD: Model for End-Stage Liver Disease. PRCs: packed red cells.